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Isotype-Restricted Corepressor Recruitment: a Constitutively Closed Helix 12 Conformation in Retinoic Acid Receptors β and γ Interferes with Corepressor Recruitment and Prevents Transcriptional Repression

Retinoic acid receptors (RARs) are ligand-regulated transcription factors that play multiple roles in vertebrate development and differentiation. RARs as a class are capable of both repressing and activating target gene expression. Transcriptional repression is mediated through the recruitment of co...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Farboud, Behnom, Hauksdottir, Herborg, Wu, Yun, Privalsky, Martin L.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12665583/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.8.2844-2858.2003
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