Lymphocyte Chemotaxis Is Regulated by Histone Deacetylase 6, Independently of Its Deacetylase Activity

In this work, the role of HDAC6, a type II histone deacetylase with tubulin deacetylase activity, in lymphocyte polarity, motility, and transmigration was explored. HDAC6 was localized at dynamic subcellular structures as leading lamellipodia and the uropod in migrating T-cells. However, HDAC6 activ...

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Detaylı Bibliyografya
Asıl Yazarlar: Cabrero, J. Román, Serrador, Juan M., Barreiro, Olga, Mittelbrunn, María, Naranjo-Suárez, Salvador, Martín-Cófreces, Noa, Vicente-Manzanares, Miguel, Mazitschek, Ralph, Bradner, James E., Ávila, Jesús, Valenzuela-Fernández, Agustín, Sánchez-Madrid, Francisco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2006
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525231/
https://ncbi.nlm.nih.gov/pubmed/16738306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-01-0008
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