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Rifampin Followed by Ceftriaxone for Experimental Meningitis Decreases Lipoteichoic Acid Concentrations in Cerebrospinal Fluid and Reduces Neuronal Damage in Comparison to Ceftriaxone Alone

Rifampin (RIF) releases smaller quantities of lipoteichoic acids (LTAs) from Streptococcus pneumoniae than ceftriaxone (CRO). Due to the rapid development of resistance, RIF cannot be used as a single agent for therapy of bacterial meningitis. For this reason, we compared the effect of treatment wit...

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Библиографические подробности
Главные авторы: Gerber, Joachim, Pohl, Karin, Sander, Valeska, Bunkowski, Stephanie, Nau, Roland
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC152510/
https://ncbi.nlm.nih.gov/pubmed/12654664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1313-1317.2003
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