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Rifampin Followed by Ceftriaxone for Experimental Meningitis Decreases Lipoteichoic Acid Concentrations in Cerebrospinal Fluid and Reduces Neuronal Damage in Comparison to Ceftriaxone Alone

Rifampin (RIF) releases smaller quantities of lipoteichoic acids (LTAs) from Streptococcus pneumoniae than ceftriaxone (CRO). Due to the rapid development of resistance, RIF cannot be used as a single agent for therapy of bacterial meningitis. For this reason, we compared the effect of treatment wit...

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Autors principals: Gerber, Joachim, Pohl, Karin, Sander, Valeska, Bunkowski, Stephanie, Nau, Roland
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152510/
https://ncbi.nlm.nih.gov/pubmed/12654664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1313-1317.2003
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