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Rifampin Followed by Ceftriaxone for Experimental Meningitis Decreases Lipoteichoic Acid Concentrations in Cerebrospinal Fluid and Reduces Neuronal Damage in Comparison to Ceftriaxone Alone

Rifampin (RIF) releases smaller quantities of lipoteichoic acids (LTAs) from Streptococcus pneumoniae than ceftriaxone (CRO). Due to the rapid development of resistance, RIF cannot be used as a single agent for therapy of bacterial meningitis. For this reason, we compared the effect of treatment wit...

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Main Authors: Gerber, Joachim, Pohl, Karin, Sander, Valeska, Bunkowski, Stephanie, Nau, Roland
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC152510/
https://ncbi.nlm.nih.gov/pubmed/12654664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1313-1317.2003
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