Rifampin Followed by Ceftriaxone for Experimental Meningitis Decreases Lipoteichoic Acid Concentrations in Cerebrospinal Fluid and Reduces Neuronal Damage in Comparison to Ceftriaxone Alone

Rifampin (RIF) releases smaller quantities of lipoteichoic acids (LTAs) from Streptococcus pneumoniae than ceftriaxone (CRO). Due to the rapid development of resistance, RIF cannot be used as a single agent for therapy of bacterial meningitis. For this reason, we compared the effect of treatment wit...

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Main Authors: Gerber, Joachim, Pohl, Karin, Sander, Valeska, Bunkowski, Stephanie, Nau, Roland
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152510/
https://ncbi.nlm.nih.gov/pubmed/12654664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1313-1317.2003
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