Combination of Daptomycin plus Ceftriaxone Is More Active than Vancomycin plus Ceftriaxone in Experimental Meningitis after Addition of Dexamethasone

We examined the cerebrospinal fluid penetration of daptomycin after the addition of dexamethasone and its bactericidal efficacy with and without ceftriaxone in an experimental rabbit model of pneumococcal meningitis. The combination of daptomycin with ceftriaxone was the most efficacious regimen for...

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Detalhes bibliográficos
Main Authors: Egermann, U., Stanga, Z., Ramin, A., Acosta, F., Stucki, A., Gerber, P., Cottagnoud, M., Cottagnoud, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704679/
https://ncbi.nlm.nih.gov/pubmed/19364870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00952-08
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