Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA(1)) in mammalian cells

We show that LPA(1) (lysophosphatidic acid receptor-1) is constitutively localized in the nucleus of mammalian cells. LPA(1) also traffics from cell membranes to the nucleus in response to LPA (lysophosphatidic acid). Several lines of evidence suggest an important role for cell-matrix interaction in...

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Autors principals: Waters, Catherine M., Saatian, Bahman, Moughal, Noreen A., Zhao, Yutong, Tigyi, Gabor, Natarajan, Viswanathan, Pyne, Susan, Pyne, Nigel J.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525019/
https://ncbi.nlm.nih.gov/pubmed/16716145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060155
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