Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

Psoriasis is a common skin disease, the pathogenesis of which has not yet been resolved. In mice, epidermis-specific deletion of inhibitor of NF-κB (IκB) kinase 2 (IKK2) results in a skin phenotype that mimics human psoriasis in several aspects. Like psoriasis, this skin disease shows pronounced imp...

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Główni autorzy: Stratis, Athanasios, Pasparakis, Manolis, Rupec, Rudolf A., Markur, Doreen, Hartmann, Karin, Scharffetter-Kochanek, Karin, Peters, Thorsten, van Rooijen, Nico, Krieg, Thomas, Haase, Ingo
Format: Artigo
Język:Inglês
Wydane: American Society for Clinical Investigation 2006
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525004/
https://ncbi.nlm.nih.gov/pubmed/16886058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27179
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