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Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

BACKGROUND: Disrupting the balance of histone lysine methylation alters the expression of genes involved in tumorigenesis including proto-oncogenes and cell cycle regulators. Methylation of lysine residues is commonly catalyzed by a family of proteins that contain the SET domain. Here, we report the...

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Bibliografiska uppgifter
Huvudupphovsmän: Brown, Mark A, Sims, Robert J, Gottlieb, Paul D, Tucker, Philip W
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524980/
https://ncbi.nlm.nih.gov/pubmed/16805913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-26
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