Tissue Penetration by Ertapenem, a Parenteral Carbapenem Administered Once Daily, in Suction-Induced Skin Blister Fluid in Healthy Young Volunteers

The penetration of 1 g of intravenous ertapenem once daily for 3 days in suction-induced skin blisters was evaluated. Ten forearm blisters were formed (n = 12) 12 h prior to the last dose. Concentrations of ertapenem in blister fluid exceeded 4 μg/ml (the MIC at which 90% of the isolates tested are...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Laethem, T., De Lepeleire, I., McCrea, J., Zhang, J., Majumdar, A., Musson, D., Rogers, D., Li, S., Guillaume, M., Parneix-Spake, A., Deutsch, P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1439-1442.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!