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CD8 T cell competition for dendritic cells in vivo is an early event in activation

T cell responses against an antigen are often focused on a small fraction of potentially immunogenic determinants, a phenomenon known as immunodominance. Immunodominance can be established at several stages of antigen presentation, including antigen processing, binding of peptides to MHC, and compet...

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Bibliographic Details
Main Authors: Willis, Richard A., Kappler, John W., Marrack, Philippa C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524925/
https://ncbi.nlm.nih.gov/pubmed/16880405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605130103
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