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AUG sequences are required to sustain nonsense-codon-mediated suppression of splicing
More than 90% of human genes are rich in intronic latent 5′ splice sites whose utilization in pre-mRNA splicing would introduce in-frame stop codons into the resultant mRNAs. We have therefore hypothesized that suppression of splicing (SOS) at latent 5′ splice sites regulates alternative 5′ splice s...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1524910/ https://ncbi.nlm.nih.gov/pubmed/16855285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl390 |
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