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The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity

In vivo the poly(A) signal not only directs 3′-end processing but also controls the rate and extent of transcription. Thus, upon crossing the poly(A) signal RNA polymerase II first pauses and then terminates. We show that the G/U-rich region of the poly(A) signal, although required for termination i...

詳細記述

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書誌詳細
主要な著者: Nag, Anita, Narsinh, Kazim, Kazerouninia, Amir, Martinson, Harold G.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524889/
https://ncbi.nlm.nih.gov/pubmed/16775304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.103206
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