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Transcripts synthesized by RNA polymerase III can be polyadenylated in an AAUAAA-dependent manner

It is well known that nearly all eukaryotic mRNAs contain a 3′ poly(A) tail. A polyadenylation signal (AAUAAA) nearby the 3′ end of pre-mRNA is required for poly(A) synthesis. The protein complex involved in the pre-mRNA polyadenylation is coupled with RNA polymerase II during the transcription of a...

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Auteurs principaux: Borodulina, Olga R., Kramerov, Dmitri A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525947/
https://ncbi.nlm.nih.gov/pubmed/18658125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1006608
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