Mechanism of Poly(A) Signal Transduction to RNA Polymerase II In Vitro

Termination of transcription by RNA polymerase II usually requires the presence of a functional poly(A) site. How the poly(A) site signals its presence to the polymerase is unknown. All models assume that the signal is generated after the poly(A) site has been extruded from the polymerase, but this...

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Autores principales: Tran, Dong P., Kim, Steven J., Park, Noh Jin, Jew, Tiffany M., Martinson, Harold G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC99921/
https://ncbi.nlm.nih.gov/pubmed/11585929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7495-7508.2001
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