p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

Interactions between the p53 and PI3K/AKT pathways play a significant role in the determination of cell death/survival. In benign cells these pathways are interrelated through the transcriptional regulation of PTEN by p53, which is required for p53-mediated apoptosis. PTEN exerts its effects by decr...

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Detalhes bibliográficos
Main Authors: Singh, Bhuvanesh, Reddy, Pabbathi G., Goberdhan, Andy, Walsh, Christine, Dao, Su, Ngai, Ivan, Chou, Ting Chao, O-charoenrat, Pornchai, Levine, Arnold J., Rao, Pulivarthi H., Stoffel, Archontoula
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152354/
https://ncbi.nlm.nih.gov/pubmed/11959846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.973602
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