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Costimulation couture: a designer approach to regulating autoimmunity

Negative or inhibitory costimulatory pathways regulate T cell activation and play a role in peripheral tolerance. Targeting these pathways harnesses the physiologic mechanisms of regulating autoimmunity and could prove beneficial for the therapy of autoimmune diseases. However, attempts at targeting...

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Detalhes bibliográficos
Main Authors: Ansari, Mohammed Javeed, Sayegh, Mohamed H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523390/
https://ncbi.nlm.nih.gov/pubmed/16886054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29455
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