High-throughput approach for detection of DNA bending and flexibility based on cyclization
We have developed a high-throughput approach to the labor-intensive problems of DNA cyclization, which we use to characterize DNA curvature and mechanical properties. The method includes a combinatorial approach to make the DNA constructs needed and automated real-time measurement of the kinetics us...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12629220/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0530189100 |
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