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Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain
Ste5, the prototypic mitogen-activated protein kinase (MAPK) scaffold protein, associates with plasma membrane-tethered Gβγ freed upon pheromone receptor occupancy, thereby initiating downstream signaling. We demonstrate that this interaction and membrane binding of an N-terminal amphipathic α-helix...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1522084/ https://ncbi.nlm.nih.gov/pubmed/16847350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1413706 |
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