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Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling

During response of budding yeast to peptide mating pheromone, the cell becomes markedly polarized and MAPK scaffold protein Ste5 localizes to the resulting projection (shmoo tip). We demonstrated before that this recruitment is essential for sustained MAPK signaling and requires interaction of a ple...

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Detalhes bibliográficos
Main Authors: Garrenton, Lindsay S., Stefan, Christopher J., McMurray, Michael A., Emr, Scott D., Thorner, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900652/
https://ncbi.nlm.nih.gov/pubmed/20547860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005817107
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