Consequences of DNA-Dependent Protein Kinase Catalytic Subunit Deficiency on Recombinant Adeno-Associated Virus Genome Circularization and Heterodimerization in Muscle Tissue

Circular concatemerization of the recombinant adeno-associated virus (rAAV) genome has been suggested as the predominant process facilitating long-term rAAV transduction in muscle. A recent study (S. Song, P. J. Laipis, K. I. Berns, and T. R. Flotte, Proc. Natl. Acad. Sci. USA 98:4084-4088, 2001) wi...

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Pubblicato in:	J Virol
Autori principali:	Duan, Dongsheng, Yue, Yongping, Engelhardt, John F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Gene Therapy
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.4751-4759.2003
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