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Expression of Helicobacter pylori Vacuolating Toxin in Escherichia coli

VacA is a secreted toxin that plays a role in Helicobacter pylori colonization of the stomach and that contributes to the pathogenesis of peptic ulcer disease. Studies of VacA structure and function have been hindered by the lack of an efficient system for expression and genetic manipulation of this...

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Bibliographic Details
Main Authors: McClain, Mark S., Cover, Timothy L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152094/
https://ncbi.nlm.nih.gov/pubmed/12654854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2266-2271.2003
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