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Pneumococcal Behavior and Host Responses during Bronchopneumonia Are Affected Differently by the Cytolytic and Complement-Activating Activities of Pneumolysin

Pneumolysin, a multifunctional toxin produced by all clinical isolates of Streptococcus pneumoniae, is strongly implicated in the pathogenesis of pneumococcal bronchopneumonia and septicemia. Using isogenic mutant strains, we examined the effect of deletion of the cytotoxic activity or complement-ac...

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Sonraí Bibleagrafaíochta
Main Authors: Jounblat, Rania, Kadioglu, Aras, Mitchell, Tim J., Andrew, Peter W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152068/
https://ncbi.nlm.nih.gov/pubmed/12654795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1813-1819.2003
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