Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants

Rapid production of protein-based tumor-specific vaccines for the treatment of malignancies is possible with the plant-based transient expression system described here. We created a modified tobamoviral vector that encodes the idiotype-specific single-chain Fv fragment (scFv) of the immunoglobulin f...

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Detalhes bibliográficos
Main Authors: McCormick, Alison A., Kumagai, Monto H., Hanley, Kathleen, Turpen, Thomas H., Hakim, Itzhak, Grill, Laurence K., Tusé, Daniel, Levy, Shoshana, Levy, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15200/
https://ncbi.nlm.nih.gov/pubmed/9892697
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