Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

Human neutrophil peptide (HNP) defensins were studied to determine their potential effects on adaptive mucosal immunity. Intranasal delivery of HNPs plus ovalbumin (OVA) enhanced OVA-specific serum IgG antibody (Ab) responses. However, OVA-specific IgA Abs were not induced in mucosal secretions or i...

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Bibliographic Details
Main Authors: Lillard, James W., Boyaka, Prosper N., Chertov, Oleg, Oppenheim, Joost J., McGhee, Jerry R.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15191/
https://ncbi.nlm.nih.gov/pubmed/9892688
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