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Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

Human neutrophil peptide (HNP) defensins were studied to determine their potential effects on adaptive mucosal immunity. Intranasal delivery of HNPs plus ovalbumin (OVA) enhanced OVA-specific serum IgG antibody (Ab) responses. However, OVA-specific IgA Abs were not induced in mucosal secretions or i...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lillard, James W., Boyaka, Prosper N., Chertov, Oleg, Oppenheim, Joost J., McGhee, Jerry R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15191/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.651
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