Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor

Prostaglandin E(2) (PGE(2)), a major COX metabolite, plays important roles in several facets of tumor biology. We characterized the contribution of the PGE(2) EP2 receptor to cancer-associated immune deficiency using EP2(–/–) mice. EP2(–/–) mice exhibited significantly attenuated tumor growth and lo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Li, Yamagata, Noboru, Yadav, Rajwardhan, Brandon, Suzanne, Courtney, Regina L., Morrow, Jason D., Shyr, Yu, Boothby, Mark, Joyce, Sebastian, Carbone, David P., Breyer, Richard M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2003
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC151895/
https://ncbi.nlm.nih.gov/pubmed/12618527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316492
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