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Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
High-throughput screening (HTS) of chemical compounds to identify modulators of molecular targets is a mainstay of pharmaceutical development. Increasingly, HTS is being used to identify chemical probes of gene, pathway, and cell functions, with the ultimate goal of comprehensively delineating relat...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2006
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1518803/ https://ncbi.nlm.nih.gov/pubmed/16864780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604348103 |
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