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A High-Throughput Migration Assay Reveals HER2-Mediated Cell Migration Arising from Increased Directional Persistence

Human epidermal growth factor receptor 2 (HER2) overexpression has been associated with increased invasiveness in mammalian breast cancer cell lines, but the effects of overexpression on key underlying cell migration properties such as translational speed and directional persistence are not understo...

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Hlavní autoři: Kumar, Neil, Zaman, Muhammad H., Kim, Hyung-Do, Lauffenburger, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518637/
https://ncbi.nlm.nih.gov/pubmed/16782798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088898
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