A High-Throughput Migration Assay Reveals HER2-Mediated Cell Migration Arising from Increased Directional Persistence

Human epidermal growth factor receptor 2 (HER2) overexpression has been associated with increased invasiveness in mammalian breast cancer cell lines, but the effects of overexpression on key underlying cell migration properties such as translational speed and directional persistence are not understo...

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Bibliographic Details
Main Authors: Kumar, Neil, Zaman, Muhammad H., Kim, Hyung-Do, Lauffenburger, Douglas A.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2006
Subjects:
Biophysical Letters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518637/
https://ncbi.nlm.nih.gov/pubmed/16782798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088898
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