Massive hepatic apoptosis associated with TGF-β1 activation after Fas ligand treatment of IGF binding protein-1–deficient mice

Acute liver failure caused by viral hepatitis or toxic damage involves both apoptotic and necrotic pathways. IGF binding protein-1 (IGFBP-1), a hepatocyte-derived secreted protein, is required for normal liver regeneration. To determine whether IGFBP-1 could prevent liver injury that entails direct...

Descripció completa

Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Leu, Julia I., Crissey, Mary Ann S., Taub, Rebecca
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2003
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12511596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16712
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!