Rapid In Vivo Screening of Experimental Drugs for Tuberculosis Using Gamma Interferon Gene-Disrupted Mice

We have developed a rapid new in vivo method for screening experimental drugs for their activity against Mycobacterium tuberculosis by using the gamma interferon gene-disrupted (GKO) C57BL/6 mouse. Due to the rapid growth of the infection, statistical differences indicating positive efficacy of acti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lenaerts, Anne J. M., Gruppo, Veronica, Brooks, Jason V., Orme, Ian M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC151769/
https://ncbi.nlm.nih.gov/pubmed/12543692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.783-785.2003
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