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Rapid In Vivo Screening of Experimental Drugs for Tuberculosis Using Gamma Interferon Gene-Disrupted Mice

We have developed a rapid new in vivo method for screening experimental drugs for their activity against Mycobacterium tuberculosis by using the gamma interferon gene-disrupted (GKO) C57BL/6 mouse. Due to the rapid growth of the infection, statistical differences indicating positive efficacy of acti...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Lenaerts, Anne J. M., Gruppo, Veronica, Brooks, Jason V., Orme, Ian M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.783-785.2003
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