Lamivudine Can Exert a Modest Antiviral Effect against Human Immunodeficiency Virus Type 1 Containing the M184V Mutation

The M184V mutation in human immunodeficiency virus (HIV) reverse transcriptase is associated with high-level resistance to both (−)2′,3′-dideoxy-3′-thiacytidine (3TC) and (−)2′,3′-dideoxy-5-fluoro-3′-thiacytidine as well as low-level resistance to 2′,3′-dideoxyinosine, 2′,3′-dideoxycytidine, and aba...

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Autores principales: Quan, Yudong, Brenner, Bluma G., Oliveira, Maureen, Wainberg, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC151747/
https://ncbi.nlm.nih.gov/pubmed/12543687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.747-754.2003
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