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Suboptimal Antibiotic Dosage as a Risk Factor for Selection of Penicillin-Resistant Streptococcus pneumoniae: In Vitro Kinetic Model

Optimizing pharmacokinetic/pharmacodynamic indices of antibiotics to obtain clinical and microbiological efficacy is essential, but dosing regimens must also be tailored to minimize the risk for emergence of resistance. The aim of the present study was to investigate whether certain concentrations o...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Odenholt, Inga, Gustafsson, Ingegerd, Löwdin, Elisabeth, Cars, Otto
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.518-523.2003
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