In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes

Genes encoding rRNA are multicopy and thus could be regulated by changing the number of active genes or by changing the transcription rate per gene. We tested the hypothesis that the number of open genes is limiting rRNA synthesis by using an electron microscopy method that allows direct counting of...

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Autores principales: French, Sarah L., Osheim, Yvonne N., Cioci, Francesco, Nomura, Masayasu, Beyer, Ann L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC151703/
https://ncbi.nlm.nih.gov/pubmed/12588976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1558-1568.2003
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