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In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes

Genes encoding rRNA are multicopy and thus could be regulated by changing the number of active genes or by changing the transcription rate per gene. We tested the hypothesis that the number of open genes is limiting rRNA synthesis by using an electron microscopy method that allows direct counting of...

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發表在:Mol Cell Biol
Principais autores: French, Sarah L., Osheim, Yvonne N., Cioci, Francesco, Nomura, Masayasu, Beyer, Ann L.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2003
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1558-1568.2003
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