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In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes

Genes encoding rRNA are multicopy and thus could be regulated by changing the number of active genes or by changing the transcription rate per gene. We tested the hypothesis that the number of open genes is limiting rRNA synthesis by using an electron microscopy method that allows direct counting of...

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Udgivet i:Mol Cell Biol
Principais autores: French, Sarah L., Osheim, Yvonne N., Cioci, Francesco, Nomura, Masayasu, Beyer, Ann L.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1558-1568.2003
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