A Methyltransferase Targeting Assay Reveals Silencer-Telomere Interactions in Budding Yeast
We have designed a modified version of the Dam identification technique and used it to probe higher-order chromatin structure in Saccharomyces cerevisiae. We fused the bacterial DNA methyltransferase Dam to the DNA-binding domain of TetR and targeted the resulting chimera to Tet operators inserted i...
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| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1498-1508.2003 |
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