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Loss of Protooncogene c-Myc Function Impedes G(1) Phase Progression Both before and after the Restriction Point

c-myc is an important protooncogene whose misregulation is believed to causally affect the development of numerous human cancers. c-myc null rat fibroblasts are viable but display a severe (two- to threefold) retardation of proliferation. The rates of RNA and protein synthesis are reduced by approxi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Biol Cell
Principais autores: Schorl, Christoph, Sedivy, John M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Cell Biology 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12631706/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-10-0649
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