Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.
We have studied the genomic organization of the c-myc locus (MYC) from 121 human primary breast carcinomas. Two types of alterations were observed: (i) the c-myc protooncogene appeared to be amplified 2- to 15-fold in 38 (32%) of the carcinoma DNAs and (ii) a non-germ-line c-myc-related fragment of...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4834 |
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