Loss of Protooncogene c-Myc Function Impedes G(1) Phase Progression Both before and after the Restriction Point
c-myc is an important protooncogene whose misregulation is believed to causally affect the development of numerous human cancers. c-myc null rat fibroblasts are viable but display a severe (two- to threefold) retardation of proliferation. The rates of RNA and protein synthesis are reduced by approxi...
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| Udgivet i: | Mol Biol Cell |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Cell Biology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12631706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-10-0649 |
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