Peptides identify multiple hotspots within the ligand binding domain of the TNF receptor 2

BACKGROUND: Hotspots are defined as the minimal functional domains involved in protein:protein interactions and sufficient to induce a biological response. RESULTS: Here we describe the use of complex and high diversity phage display libraries to isolate peptides (called Hotspot Ligands or HSPLs) wh...

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Bibliografiska uppgifter
Huvudupphovsmän: Hsiao, Ku-chuan, Brissette, Renee E, Wang, Pinger, Fletcher, Paul W, Rodriguez, Vanessa, Lennick, Michael, Blume, Arthur J, Goldstein, Neil I
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2003
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC151557/
https://ncbi.nlm.nih.gov/pubmed/12646066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-1-1
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