Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation
Hypoxia, reoxygenation, and the tyrosine phosphatase inhibitor pervanadate activate the transcription factor NF-κB, involving phosphorylation of its inhibitor IκB-α on tyrosine 42. This modification does not lead to degradation of IκB by the proteasome/ubiquitin pathway, as is seen on stimulation of...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15153/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.429 |
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