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Extracellular Matrix Enhances Heregulin-Dependent BRCA1 Phosphorylation and Suppresses BRCA1 Expression through Its C Terminus

Germ line mutations in the breast cancer susceptibility gene BRCA1 account for the increased risk of early onset of familial breast cancer, whereas overexpression of the ErbB family of receptor tyrosine kinases has been linked to the development of nonfamilial or sporadic breast cancer. To analyze w...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Miralem, Tiho, Avraham, Hava Karsenty
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.579-593.2003
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