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Extracellular Matrix Enhances Heregulin-Dependent BRCA1 Phosphorylation and Suppresses BRCA1 Expression through Its C Terminus

Germ line mutations in the breast cancer susceptibility gene BRCA1 account for the increased risk of early onset of familial breast cancer, whereas overexpression of the ErbB family of receptor tyrosine kinases has been linked to the development of nonfamilial or sporadic breast cancer. To analyze w...

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Autors principals: Miralem, Tiho, Avraham, Hava Karsenty
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151527/
https://ncbi.nlm.nih.gov/pubmed/12509456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.579-593.2003
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