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RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

Influenza A virus causes widespread infection in the human respiratory tract, but existing vaccines and drug therapy are of limited value. Here we show that short interfering RNAs (siRNAs) specific for conserved regions of the viral genome can potently inhibit influenza virus production in both cell...

詳細記述

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書誌詳細
主要な著者: Ge, Qing, McManus, Michael T., Nguyen, Tam, Shen, Ching-Hung, Sharp, Phillip A., Eisen, Herman N., Chen, Jianzhu
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC151407/
https://ncbi.nlm.nih.gov/pubmed/12594334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437841100
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