T cell receptor (TCR) α/δ locus enhancer identity and position are critical for the assembly of TCR δ and α variable region genes

T cell receptor (TCR) δ and α variable region genes are assembled from germ-line gene segments located in a single chromosomal locus in which TCRδ segments are situated between TCRα segments. The TCRα enhancer (Eα) located at the 3′ end of the TCRα/δ locus functions over a long chromosomal distance...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Bassing, Craig H., Tillman, Robert E., Woodman, Barbara B., Canty, David, Monroe, Robert J., Sleckman, Barry P., Alt, Frederick W.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437943100
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