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T cell receptor (TCR) α/δ locus enhancer identity and position are critical for the assembly of TCR δ and α variable region genes

T cell receptor (TCR) δ and α variable region genes are assembled from germ-line gene segments located in a single chromosomal locus in which TCRδ segments are situated between TCRα segments. The TCRα enhancer (Eα) located at the 3′ end of the TCRα/δ locus functions over a long chromosomal distance...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Bassing, Craig H., Tillman, Robert E., Woodman, Barbara B., Canty, David, Monroe, Robert J., Sleckman, Barry P., Alt, Frederick W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437943100
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