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Xenopus laevis CYP17 Regulates Androgen Biosynthesis Independent of the Cofactor Cytochrome b(5)

The enzyme CYP17 primarily regulates androgen production by mediating four reactions: conversion of pregnenolone and progesterone to 17-hydroxypregnenolone and 17-hydroxyprogesterone, respectively (17α-hydroxylase activity), followed by conversion of the 17-hydroxylated steroids to dehydroepiandrost...

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Hlavní autoři: Yang, Wei-Hsiung, Hammes, Stephen R
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513634/
https://ncbi.nlm.nih.gov/pubmed/15640159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411886200
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