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Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing

Transcriptional elongation and termination by RNA polymerase (RNAP) are controlled by interactions among the nascent RNA, DNA, and RNAP that comprise the ternary transcription elongation complex (TEC). To probe the effects of co-transcriptionally-folded RNA hairpins on elongation as well as the stab...

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Autori principali: Dalal, Ravindra V., Larson, Matthew H., Neuman, Keir C., Gelles, Jeff, Landick, Robert, Block, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513632/
https://ncbi.nlm.nih.gov/pubmed/16857589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.06.023
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