Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

Binding specificity between fibroblast growth factors (FGFs) and their receptors (FGFRs) is essential for mammalian development and is regulated primarily by two alternatively spliced exons, IIIb (“b”) and IIIc (“c”), that encode the second half of Ig-like domain 3 (D3) of FGFRs. FGF7 and FGF10 acti...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Yeh, Brian K., Igarashi, Makoto, Eliseenkova, Anna V., Plotnikov, Alexander N., Sher, Ifat, Ron, Dina, Aaronson, Stuart A., Mohammadi, Moosa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436500100
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